{"id":3389,"date":"2017-09-30T12:49:34","date_gmt":"2017-09-30T12:49:34","guid":{"rendered":"http:\/\/sites.cardiff.ac.uk\/kille-morgan\/?page_id=3389"},"modified":"2017-12-23T16:48:45","modified_gmt":"2017-12-23T16:48:45","slug":"mint","status":"publish","type":"page","link":"http:\/\/sites.cardiff.ac.uk\/kille-morgan\/projects\/mint\/","title":{"rendered":"MINT- Metal Ion and Nanoparticle Trafficking in Terrestrial Isopods"},"content":{"rendered":"<figure class=\"image\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" class=\"alignleft\" src=\"https:\/\/i0.wp.com\/sites.cardiff.ac.uk\/kille-morgan\/files\/2017\/09\/LOGO-MINT2.png?resize=130%2C129\" alt=\"\" width=\"130\" height=\"129\" \/><\/p>\n<h2><\/h2>\n<\/figure>\n<ul>\n<li>Principal Investigator: <a href=\"http:\/\/www.cardiff.ac.uk\/people\/view\/772413-ferreira-nuno\">Dr. Nuno Ferreira<\/a> \u2013 Cardiff School of Biosciences<\/li>\n<li>CO-Principal Investigator: \u00a0<a title=\"Pete Kille\" href=\"http:\/\/sites.cardiff.ac.uk\/kille-morgan\/the-team\/profpkille\/\">Dr Peter Kille<\/a> \u2013 Cardiff School of Biosciences<\/li>\n<li>Colaborators: <a href=\"https:\/\/www.cardiff.ac.uk\/people\/view\/81012-cunha-luis\">Dr. Lu\u00eds Cunha<\/a> \u2013 Cardiff School of Biosciences;\u00a0<a href=\"http:\/\/www.cesam.ua.pt\/migueloliveira\">Dr. Miguel Oliveira<\/a> \u2013 Univ. Aveiro, <a href=\"https:\/\/sigarra.up.pt\/ciimar\/funcionarios_geral.formview?p_codigo=37764\">Dr. Laura Guimar\u00e3es<\/a> \u2013 CIIMAR (list under update)<\/li>\n<li>Funder: S\u00ear Cymru MSCA COFUND Fellowship founded by Cardiff University, Welsh Government and EU<\/li>\n<\/ul>\n<h3>Abstract<\/h3>\n<p>EU policies (i.e. REACH or RIPoN) and Horizon 2020 define within their priorities the research and development of nanotechnologies along with the evaluation of their ecotoxicological effects. The exponential exploitation of nanotechnologies has resulted in the release of a diverse range of nanoparticles into the environment. The knowledge-base used by legislators and environmental regulators to perform risk assessment on the interaction between the Environment and NPs is scarce especially given the continual generation of new NPs. This project <strong>aims to<\/strong> <strong>proactively evaluate the biological impact of new generations of nickel- and gold- NPs <\/strong>with significant future commercial potential<strong> exploiting the elegant and highly specific metal trafficking system of the terrestrial isopod hepatopancreas (HP)<\/strong> in <em>Oniscus asellus. <\/em>The project will determine how metals are trafficked, \u2018who\u2019 are the major players (proteins and small molecules) are in the process and the impact of these NPs on the basal metallo-biology or this organism. The project will focus on the <strong>development of a spatially resolved holistic understanding<\/strong> of <strong>metal trafficking pathways<\/strong> within <strong>the terrestrial isopods<\/strong> by targeting <strong>different levels of biological organization<\/strong> (molecular and cellular physiology) and how the NPs impact the homeostatic systems.<\/p>\n<p>&nbsp;<\/p>\n<h3>Oportunities:<\/h3>\n<p>If you are interested in doing\u00a0 a PhD at Cardiff University in a topic related to this project please visit:<\/p>\n<p><a href=\"http:\/\/www.cardiff.ac.uk\/study\/postgraduate\/research\/programmes\/project\/the-terrestrial-isopod-holobiont-exploring-the-role-of-the-hepatopancreal-microbiome-in-isopod-adaptation-to-metal-contamination\">http:\/\/www.cardiff.ac.uk\/study\/postgraduate\/research\/programmes\/project\/the-terrestrial-isopod-holobiont-exploring-the-role-of-the-hepatopancreal-microbiome-in-isopod-adaptation-to-metal-contamination<\/a><\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Principal Investigator: Dr. Nuno Ferreira \u2013 Cardiff School of Biosciences CO-Principal Investigator: \u00a0Dr Peter Kille \u2013 Cardiff School of Biosciences Colaborators: Dr. Lu\u00eds Cunha \u2013 Cardiff School of Biosciences;\u00a0Dr. Miguel Oliveira \u2013 Univ. Aveiro, Dr. Laura Guimar\u00e3es \u2013 CIIMAR (list under update) Funder: S\u00ear Cymru MSCA COFUND Fellowship founded by Cardiff University, Welsh Government and<\/p>\n","protected":false},"author":7003,"featured_media":0,"parent":827,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"jetpack_post_was_ever_published":false,"footnotes":""},"class_list":["post-3389","page","type-page","status-publish","hentry"],"jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/P6t6rP-SF","meta_box":[],"_links":{"self":[{"href":"http:\/\/sites.cardiff.ac.uk\/kille-morgan\/wp-json\/wp\/v2\/pages\/3389","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/sites.cardiff.ac.uk\/kille-morgan\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"http:\/\/sites.cardiff.ac.uk\/kille-morgan\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"http:\/\/sites.cardiff.ac.uk\/kille-morgan\/wp-json\/wp\/v2\/users\/7003"}],"replies":[{"embeddable":true,"href":"http:\/\/sites.cardiff.ac.uk\/kille-morgan\/wp-json\/wp\/v2\/comments?post=3389"}],"version-history":[{"count":7,"href":"http:\/\/sites.cardiff.ac.uk\/kille-morgan\/wp-json\/wp\/v2\/pages\/3389\/revisions"}],"predecessor-version":[{"id":3416,"href":"http:\/\/sites.cardiff.ac.uk\/kille-morgan\/wp-json\/wp\/v2\/pages\/3389\/revisions\/3416"}],"up":[{"embeddable":true,"href":"http:\/\/sites.cardiff.ac.uk\/kille-morgan\/wp-json\/wp\/v2\/pages\/827"}],"wp:attachment":[{"href":"http:\/\/sites.cardiff.ac.uk\/kille-morgan\/wp-json\/wp\/v2\/media?parent=3389"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}