Key Publications

Higgs et al. The parenting hub of the hypothalamus is a focus of imprinted gene action PLoS Genetics doi:10.1371/journal.pgen.1010961 (2023)

John et al. Imprinted genes and the manipulation of parenting in mammals Nature Reviews Genetics 24:783-796 (2023)

Steventon et al. Menopause age, reproductive span and hormone therapy duration predict the volume of medial temporal lobe brain structures in postmenopausal women Psychoneuroendocrinology doi:10.1016/j.psyneuen.2023.106393 (2023)

Wren et al. Characterising heart rhythm abnormalities associated with Xp22.31 deletion Journal of Medical Genetics 60(7):636-643 (2023).

Higgs et al. Systematic investigation of imprinted gene expression and enrichment in the mouse brain explored at single-cell resolution BMC Genomics doi:10.1186/s12864-022-08986-8 (2022)

Westacott et al. Complement C3 and C3aR mediate different aspects of emotional behaviours; relevance to risk for psychiatric disorder Brain Behavior and Immunity 99:70-82 (2022).

Zahova et al. Comparison of mouse models reveals a molecular distinction between psychotic illness in PWS and schizophrenia Translational Psychiatry 11(1):433 (2021)

Harrison et al. Placental endocrine insufficiency programs anxiety, deficits in cognition and atypical social behaviour in offspring Human Molecular Genetics 30(19):1863-1880 (2021)

Gubb et al. Medical and neurobehavioural phenotypes in male and female carriers of Xp22.31 duplications in the UK Biobank Human Molecular Genetics 29(17):2872-2881 (2020)

Brcic et al. Medical and neurobehavioural phenotypes in carriers of X-linked ichthyosis-associated genetic deletions in the UK Biobank Journal of Medical Genetics 57:692-698 (2020)

Davies et al. Prader-Willi syndrome imprinting centre deletion mice have impaired baseline and 5-HT2CR-mediated response inhibition Human Molecular Genetics 28(18):3013 (2019)

Silva et al. Cyfip1 haploinsufficient rats show white matter changes, myelin thinning, abnormal oligodendrocytes and behavioural inflexibility Nature Communications 10:3455 (2019)

O’Brien et al. Sex differences in gene expression in the human fetal brain bioRxiv doi:10.1101/483636 (2019)

Sykes et al. Genetic variation in the psychiatric risk gene CACNA1C modulates reversal learning across species Schizophrenia Bulletin 45(5):1024-1032 (2019)

Creeth et al. Maternal care boosted by paternal imprinting in mammals PLoS Biology 16(7):e2006599 (2018)

Dent et al. Impulsive choice in mice lacking paternal expression of Grb10 suggests intragenomic conflict in behavior Genetics 209(1):233 (2018)

Dazzan et al. Do defective immune system-mediated myelination processes increase postpartum psychosis risk? Trends in Molecular Medicine 24(11):26-34 (2018)

McNamara et al. Dopaminergic and behavioural changes in a loss-of-imprinting model of Cdkn1cGenes Brain and Behavior 17(2):149 (2017)

Garfield et al. Increased alternate splicing of Htr2c in a mouse model for Prader-Willi syndrome leads to disruption of 5HT2CR mediated appetite. Molecular Brain 9(1):95 (2016)

Isles et al. Parental Origin of Interstitial Duplications at 15q11.2-q13.3 in Schizophrenia and Neurodevelopment Disorders PLoS Genetics 12(5): e1005993 (2016)

Davies et al. Genetic and pharmacological modulation of the steroid sulfatase axis improves response control; comparison with drugs used in ADHD Neuropsychopharmacology 39(11):2622-32 (2014)

Mikaelsson et al. Placental programming of anxiety in adulthood revealed by Igf2-null models. Nature Communications 4:2311. (2013)

Garfield et al. Distinct physiological and behavioural functions for the parental alleles of the imprinted Grb10 gene Nature 469: 534-8 (2011)

Davies et al. Converging pharmacological and genetic evidence indicates a role for steroid sulfatase in attention Biological Psychiatry 66:360-7 (2009)

Davies et al. X-monosomy effects on visuospatial attention in mice: a candidate gene and implications for Turner syndrome and Attention Deficit Hyperactivity Disorder Biological Psychiatry 61(12):1351-1360 (2007)

Davies et al. Xlr3b is a new imprinted candidate for X-linked parent-of-origin effects on cognitive function in mice Nature Genetics 37:625-9 (2005)