Day: September 24, 2013

Hot Paper! UPARSE: highly accurate OTU sequences from microbial amplicon reads

Posted on 24 September 2013 by Pete

A fantastic new paper out on the UPARSE pipeline and algorithm for cleaning and clustering OTUs in microbial diversity work, from Robert C Edgar. The UPARSE pipeline reports operational taxonomic unit (OTU) sequences with ≤1% incorrect bases in artificial microbial community tests, compared with >3% incorrect bases commonly reported by other methods. Paradigm shift? http://www.nature.com/nmeth/journal/vaop/ncurrent/full/nmeth.2604.html “UPARSE
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